Fact: Here at FSMG, we suggest not using CBD products or marijuana of any kind during fertility treatment as it may affect outcome. Marijuana use has been associated with abnormal sperm counts, morphology and motility. Women undergoing fertility treatment who smoke marijuana may be at increased risk of miscarriage. Marijuana use in pregnancy may be associated with neurodevelopmental abnormalities in children.
Cannabis and Male Fertility: A Systematic Review.
Payne KS, Mazur DJ, Hotaling JM, Pastuszak AW
J Urol. 2019;202(4):674. Epub 2019 Sep 6.
PURPOSE With cannabis consumption on the rise and use prominent among males of reproductive age it is essential to understand the potential impact of cannabis on male fertility. We reviewed the literature regarding the effects of cannabis on male fertility.
MATERIALS AND METHODS We performed a literature search using PubMed®/MEDLINE® to identify relevant studies of the effects of cannabis on male fertility. Relevant studies were identified and reviewed.
RESULTS The strongest evidence of cannabis induced alterations in male fertility is in the category of semen parameters. Research supports a role for cannabis in reducing sperm count and concentration, inducing abnormalities in sperm morphology, reducing sperm motility and viability, and inhibiting capacitation and fertilizing capacity. Animal models demonstrate a role for cannabis in testicular atrophy, and reduced libido and sexual function but to our knowledge these results have not yet been replicated in human studies. Studies of hormonal changes suggest inconclusive effects on testosterone levels, lowered luteinizing hormone levels and unchanged follicle-stimulating hormone levels.
CONCLUSIONS Current research suggests that cannabis may negatively impact male fertility. Further studies are needed to validate that robust findings in animal models will carry over into human experience. Clinicians should be aware of these potential effects when prescribing medical marijuana therapies to men of reproductive age, and they should consider the degree of cannabis use as a possible component of a complete male infertility workup.
There are minimal data on the effects of recreational drug use on fertility . A study of self-reported marijuana use by individuals undergoing fertility treatment reported a higher risk of pregnancy loss in marijuana smokers compared with past or never-users (n = 308, 379 cycles, adjusted probability 54 versus 26 percent) . Unexpectedly, a higher pregnancy rate was reported for couples undergoing IVF when the male partner smoked marijuana while the female partner did not. These drugs should be avoided because of their general health risks.